If you or a loved one were diagnosed with cutaneous t-cell lymphoma after receiving a Dupixent (dupilumab) injection, you may be entitled to recover compensation from a Dupixent CTCL lymphoma lawsuit case or settlement claim.
A team of drug injury lawyers and class action attorneys is investigating potential Dupixent lawsuit cases and settlement claims of individuals who were diagnosed with cutaneous T-cell lymphoma (CTCL) after receiving Dupixent (dupilumab) injections.
Dupixent (dupilumab) is a prescription biologic (monoclonal antibody) given by subcutaneous injection (under the skin) to treat allergic diseases (e.g., atopic dermatitis, eczema, asthma and nasal polyps which result in chronic sinusitis), eosinophilic esophagitis, prurigo nodularis, chronic obstructive pulmonary disease (COPD) and other conditions.
Cutaneous T-cell lymphoma (CTCL) is a group of rare blood cancers (a form of non-Hodgkin lymphoma) in which T-lymphocytes (white blood cells used by the immune system to fight diseases) become cancerous (i.e., malignant) and attack the skin and other parts of the body.
Unfortunately, according to research studies, patients who received Dupixent injections may be at an increased risk (perhaps as much as 4 or more times more likely) of developing cutaneous T-cell lymphoma. Cancer victims and survivors (and their family members) are now coming forward and filing Dupixent lawsuits seeking compensation and justice for the harm and suffering they may have endured.
Dupixent T-Cell Lymphoma Lawsuit: Overview
- What Is a Dupixent (Dupilumab)?
- What Is Cutaneous T-cell Lymphoma (CTCL)?
- Has Dupixent Been Linked to Cutaneous T-cell Lymphoma (CTCL)?
- Who May Qualify For a Dupixent Lymphoma Lawsuit or Settlement?
- What Is The Depo-Provera Lawsuit About?
- Are Dupixent Users More Likely to Develop T-Cell Lymphoma?
- What Are Signs or Symptoms of Cutaneous T-cell Lymphoma?
- What Complications Can Cutaneous T-Cell Lymphoma Cause?
- Are There Medical Treatments for CTCL Lymphoma?
- What Companies May Be Sued For Dupixent Injuries?
- Can I Recover Compensation From a Dupixent Lymphoma Lawsuit?
- Is There A Time Limit To Filing a Dupixent Cancer Lawsuit?
- Request A Free Case Review From A Dupixent Injury Lawyer
Dupixent Lymphoma Lawsuit & Settlement Cases
Dupixent T-Cell Lymphoma lawsuit and settlement cases potentially being investigated include claims involving patients who, after receiving a Dupixent injection, were later diagnosed with T-cell lymphoma including:
- Cutaneous T-cell lymphoma (CTCL)
- Mycosis fungoides (MF)
- Lymphomatoid papulosis (LyP)
- Primary cutaneous anaplastic large cell lymphoma (PCALCL)
- Sézary syndrome (SS)
- Lymphoma of the skin
- Cutaneous T-cell non-Hodgkin lymphoma
- Skin T-cell lymphoma
- Subcutaneous panniculitis-like T-cell lymphoma (SPTCL)
- Extranodal NK/T-cell lymphoma
- Primary cutaneous gamma/delta T-cell lymphoma (PCGDTCL)
- Peripheral T-cell lymphoma (PTCL)
- Other type of T-cell lymphoma
- Other type of lymphoma blood cancer
If you or someone you love suffered from Cutaneous T-Cell Lymphoma after receiving Dupixent injections, you may be eligible to recover compensation from a Dupixent lawsuit or settlement case.
Dupixent Cancer Injury Lawsuit Complaints
Individuals who used Dupixent for conditions like eczema (atopic dermatitis), asthma, or other indications, and were later diagnosed with CTCL or other T-cell lymphoma have filed Dupixent personal injury and wrongful death lawsuits seeking justice and financial compensation.
Plaintiffs in the Dupixent cancer injury lawsuits have alleged, among other things, that they suffered from cutaneous T-cell lymphoma after receiving Dupixent (dupilumab) injections and that defendants knew, or should have known, that Dupixent could lead to an increased risk of developing CTCL but that they did not provide an adequate warning about the risks or the need for monitoring for resultant symptoms.
The Dupixent lawsuit complaints have asserted claims for, among other things, negligence, negligent failure to warn and design defect, strict liability (failure to warn), negligent misrepresentation, fraudulent misrepresentation, breach of warranty (express and implied) and, in cases involving plaintiffs who have died, wrongful death and survival claims.
Plaintiffs in Dupixent lawsuits have sought to recover compensatory damages (such as compensation for physical pain, mental suffering, inconvenience, loss of the enjoyment of life, past and future medical expenses, loss of consortium and loss of earnings and earning capacity), punitive damages, and/or attorneys’ fees and costs, among others.
Companies That May Be Sued For Dupixent Injuries
Defendants in Dupixent lawsuits have include developers, manufacturers, sellers and/or distributors of Dupixent (dupilumab), including:
- Regeneron Pharmaceuticals, Inc.
- Sanofi-Aventis U.S. LLC
- Other potential defendants
Studies Linking Dupixent Use to Blood Cancer
Several recent scientific studies and publications have found a potential link between the use of Dupixent (dupilumab) injections and an increased risk of developing cutaneous T-cell lymphoma (CTCL).
For example, a study published in the Journal of the American Academy of Dermatology (JAAD) compared people with eczema who took dupilumab to eczema patients who didn’t take dupilumab and found that the dupilumab group had higher odds of later being diagnosed with CTCL (about 4 times higher), with most CTCL diagnoses showing up more than a year after starting the drug. See Hasan I, Parsons L, Duran S, Zinn Z. Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: A retrospective cohort study. J Am Acad Dermatol. 2024 Aug;91(2):255-258. doi: 10.1016/j.jaad.2024.03.039. Epub 2024 Apr 6. PMID: 38588818.
Another study published in Dermatologic Therapy compared 19,612 dupilumab users to 19,612 non-users with eczema and found that Dupilumab users had a higher relative risk of CTCL overall (~4.6x) and that about 62% of CTCL diagnoses happened within the first year after starting dupilumab. See Mandel J, Mehta J, Hafer R, Ayub M, Nusrat F, Yang H, Porcu P, Nikbakht N. Increased Risk of Cutaneous T-Cell Lymphoma Development after Dupilumab Use for Atopic Dermatitis. Dermatol Ther. 2024 Jan;2024:9924306. doi: 10.1155/2024/9924306. Epub 2024 Aug 14. PMID: 39668908; PMCID: PMC11635927.
CTCL Lymphoma Signs & Symptoms
Signs and symptoms of cutaneous t-cell lymphoma can include:
- Flat scaly patches on skin
- Bumps on skin
- Skin rashes that last for months
- Red, pink, gray, or brown patches
- Dry skin
- Plaques (thick, raised lesions)
- Itchy skin
- Thickened skin
- Tumors/nodules on skin
- Ulcerated tumors that break open
- Lumpy growths on the skin
- Erythroderma
- Hair loss (including brows or beard areas in men)
- Thickened palms/soles with painful cracks (palmoplantar keratoderma)
- Nail changes (ridges, yellow, rough)
- Lower eyelid turns outward (ectropion)
- Enlarged lymph nodes
- Skin infections
- Hypopigmentation (patches lighter in color)
- “Lion-like” look to the face
- Fever and chills
- Unexplained weight loss
- Fatigue
- Feeling unwell (malaise)
- Pain or tenderness
- Night sweats
- Other cutaneous t-cell lymphoma symptoms or signs
The signs and symptoms of CTCL can vary widely and often mimic other common skin conditions, like eczema, psoriasis, or chronic dermatitis, which can make diagnosis of CTCL challenging.
Procedures and tests used by dermatologists, hematologists, oncologists and other physicians to diagnose cutaneous T-cell lymphoma can include a patient history, physical examination, dermoscopy; serial skin biopsies reviewed by dermatopathology; immunohistochemistry (e.g., CD2, CD3, CD4, CD7, CD8, CD30); T-cell receptor clonality testing (PCR/NGS); peripheral-blood studies (CBC, flow cytometry, Sézary cell count); imaging for staging (CT or PET/CT); and, when indicated, lymph-node or bone-marrow biopsy, among others.
Cutaneous T-cell Lymphoma Complications
CTCL can lead to serious complications including:
- Ulcerated tumors
- Progression from patches to plaques/tumors
- Ulceration and non-healing wounds
- Secondary infections (cellulitis, sepsis, disseminated herpes/zoster)
- Erythroderma (widespread, red, scaly rash covering the body)
- Fluid/protein/electrolyte loss or imbalance
- Impaired thermoregulation (hypothermia)
- Edema
- Severe pruritus
- Immune system compromise
- Physical disfigurement
- Sleep disturbance
- Emotional distress
- Psychological distress
- Neurological complications
- Large cell transformation (LCT)
- Transformation to more aggressive, high-grade lymphoma
- Spread to other organs
- Metastasis to lymph nodes
- Metastasis organs (e.g., liver, spleen, lungs, bone marrow, etc.)
- Chronic pain
- Death
- Other cutaneous t-cell lymphoma complications
The prognosis and potential for complications are highly dependent on the stage of the disease at diagnosis. Patients with early-stage disease can have a very good prognosis and a near-normal life expectancy, but those with advanced disease face more significant challenges.
Cutaneous T-cell Lymphoma Treatment
Treatment for cutaneous t-cell lymphoma can include skin-directed therapies (topical corticosteroids, topical chemotherapy such as mechlorethamine, topical retinoids, phototherapy with NB-UVB or PUVA, and localized or total-skin electron-beam radiation); systemic agents for refractory/advanced disease (bexarotene, interferon-α, low-dose methotrexate, HDAC inhibitors like vorinostat or romidepsin); targeted/immune therapies (brentuximab vedotin for CD30⁺ disease, mogamulizumab, checkpoint inhibitors in select cases); and, in some patients, allogeneic hematopoietic stem-cell transplantation.
Recover Compensation For Lymphoma Injuries
When an injury (such as cutaneous t-cell lymphoma) is caused by someone else’s negligence, victims may be entitled to financial compensation. Plaintiffs who bring Dupixent lawsuits may be able to recover money damages for harms and losses suffered as a result of their being diagnosed with CTCL, including compensation for:
- Medical expenses (past and future): Cancer victims may be entitled to compensation for all reasonable and necessary medical costs, both past and future, incurred as a result of their lymphoma diagnosis, including dermatology/oncology visits; skin biopsies and pathology; staging and monitoring (blood tests for Sézary cells, T-cell receptor studies, flow cytometry, and PET/CT or CT scans), medications, skin-directed therapies (such as phototherapy and total skin electron beam therapy) and hospitalizations for infections, flares, or complications. In some cases, recoverable costs may encompass extracorporeal photopheresis, infusion services, radiation or chemotherapy, stem-cell transplant evaluation, wound-care supplies, home-health nursing, pain management, and psychosocial support. Rehabilitation for fatigue or neuropathy, transportation to specialty centers, caregiver respite, and insurance expenses (premiums, copays, deductibles) might be included. A comprehensive oncology life-care plan may be used to project future CTCL lymphoma needs and ensure the full scope of long-term surveillance and supportive care is financially accounted for.
- Lost wages/income (past and future)/Loss of earning capacity: If lymphoma complications or treatments cause a victim to miss work, they may recover compensation for all income lost during their recovery period (e.g., lost wages, lost bonuses, commissions, and other benefits). In cases of more severe injury, where the victim cannot return to their previous occupation or work at all, compensation may also include projected future income losses. If victims experience long-term or permanent reduction in their ability to earn income that prevents a return to the same job, full-time hours, or reliable attendance, they may recover for loss of earning capacity (which considers the person’s age, disease stage and expected course, profession, skills, and likely career trajectory had the lymphoma not occurred, as well as the impact of necessary accommodations and time-intensive ongoing care. Some jobs (manual labor, outdoor work, or public-facing positions) may be especially difficult to return to due to mobility limits, infection risk, or visible skin disease.
- Pain and suffering: Lymphoma victims may be entitled to compensation for the physical pain, discomfort and suffering resulting from the cancer and related treatments. Unlike medical bills or lost income, pain and suffering damages are non-economic damages, meaning they don’t have a clear dollar amount and can vary case by case. Compensation may reflect intense and relentless itching and burning, painful or ulcerated skin lesions, infections, sleep disruption, photosensitivity from therapies, fatigue, and treatment side effects.
- Mental anguish/emotional distress: Living with a chronic cancer (and in particular one that affects appearance) can lead to anxiety, depression, social withdrawal, and fear of progression or relapse. Compensation for such psychological harm may be recoverable.
- Loss of enjoyment / quality of life: Plaintiffs with cutaneous t-cell lymphoma may no longer comfortably participate in activities or hobbies they once loved (e.g., swimming, outdoor sports, travel) due to skin pain, sun/heat sensitivity, bandaging, or self-consciousness about visible lesions. Compensation for loss of enjoyment of life aims to account for this deeply personal impact.
- Scarring/disfigurement: Persistent plaques, tumors, ulcers, and treatments can leave permanent discoloration, scarring, or changes to hair, nails, or eyelids (e.g., ectropion).
- Home-care needs: Some CTCL patients may require help with daily activities during flares or erythroderma (bathing, dressing, dressing changes, medication administration), or periodic skilled nursing for complex wound care, which may be compensable as damages.
- Out-of-pocket and incidental costs: Travel and lodging for specialty cancer centers, parking, copays/deductibles, over-the-counter creams and emollients, special clothing/bedding for sensitive skin, and home phototherapy equipment (when prescribed) may also be compensable.
- Loss of consortium: In some cases, spouses/partners may seek damages for the impact on companionship, intimacy, and household support caused by CTCL and its treatment.
- Wrongful death damages: Certain family and loved ones of individuals who may have died as a result of their lymphoma diagnosis may be able to recover financial compensation from a Dupixent wrongful death lawsuit or settlement claim. Dupixent wrongful death lawsuit damages might include, among other things, pecuniary losses suffered by a surviving spouse or next of kin of the deceased family member, such as past and future loss of money, income, benefits, goods, services, or loss of society (i.e., love, affection, care, attention, companionship, comfort, guidance, and protection).
- Other possible monetary damages: Other unique financial harms or complications tied to CTCL (e.g., prolonged hospitalizations for sepsis, vision issues from eyelid involvement, etc.) might be recoverable in a t-cell lymphoma lawsuit, depending on the particular circumstances of a case.
Time Is Limited To File A Dupixent Lawsuit
Deadlines called statutes of limitation and statutes of repose may limit the time that individuals have to file a Dupixent lawsuit to try to recover compensation for injuries they claim to have suffered (e.g., cutaneous t-cell lymphoma and related complications) after taking Dupixent.
This means that if a Dupixent lawsuit claim is not filed before the applicable deadline or limitations period, the injured party may be barred from ever pursuing litigation or taking legal action regarding their Dupixent injury claim. That is why it is important to connect with a Dupixent injury lawyer or attorney as soon as possible.
Connect With A Dupixent Injury Attorney
Navigating the aftermath of a cutaneous T-cell lymphoma diagnosis can be overwhelming for victims and their families, especially when the injury could be linked to a medication (i.e., Dupixent) that they were prescribed. A Dupixent injury attorney can help evaluate your situation, explain your options, and protect your legal rights while you focus on treatment and recovery or other things important to you.
Dupixent injury cases are handled on a contingency fee basis, meaning clients pay no attorney’s fees unless compensation is recovered by their lawyers (in which case, the attorneys get paid a percentage of the amount of any settlement or award recovered). This makes high-quality legal representation accessible to CTCL injury victims, regardless of their financial circumstances.
If you or a loved one have suffered from cutaneous t-cell lymphoma (CTCL) after receiving Dupixent injections, you may be entitled to recover compensation from a Dupixent lawsuit case or settlement claim. Contact a drug injury lawyer to request a free case review.
*If you or a loved one are experiencing health issues, side effects or complications after taking a prescription drug or medication, we urge you to promptly consult with your doctor or physician for an evaluation.
**The listing of a company (e.g., Regeneron Pharmaceuticals, Inc. and/or Sanofi-Aventis U.S. LLC) or product (e.g., Dupixent) is not meant to state or imply that the company acted illegally or improperly or that the product is unsafe or defective; rather only that an investigation may be, is or was being conducted to determine whether legal rights have been violated.
***The use of any trademarks, tradenames or service marks is solely for product identification and/or informational purposes.
Fill out the form to request a free attorney review.